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10,023 results
ConceptNode typeBase domainIdentifier
(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride
A drug that selectively activates certain subclasses of muscarinic receptors and also activates postganglionic nicotinic receptors. It is commonly us…
Organic ChemicalBiochemistryAMW:CHEM:020672
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or sy…
Organic ChemicalBiochemistryAMW:CHEM:022020
1-Acylglycerol-3-Phosphate O-Acyltransferase
An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to generate 1,2-diacyl-sn-glycerol 3-phosphate. This e…
Enzyme or CoenzymeBiochemistryAMW:CHEM:081305
1-Acylglycerophosphocholine O-Acyltransferase
An enzyme localized predominantly within the plasma membrane of lymphocytes. It catalyzes the transfer of long-chain fatty acids, preferentially unsa…
Enzyme or CoenzymeBiochemistryAMW:CHEM:081306
1-Alkyl-2-acetylglycerophosphocholine Esterase
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the bi…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080332
1-Butanol
A four carbon linear hydrocarbon that has a hydroxy group at position 1.
Organic ChemicalBiochemistryAMW:CHEM:020099
1-Carboxyglutamic Acid
Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kidney protein, in bone protein, and in the protein …
Organic ChemicalBiochemistryAMW:CHEM:020937
1-Deoxynojirimycin
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Organic ChemicalBiochemistryAMW:CHEM:021699
1-Methyl-3-isobutylxanthine
A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby ac…
Heterocyclic CompoundBiochemistryAMW:CHEM:030879
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson d…
Heterocyclic CompoundBiochemistryAMW:CHEM:030506
1-Methyl-4-phenylpyridinium
An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of c…
Heterocyclic CompoundBiochemistryAMW:CHEM:030526
1-Naphthylamine
A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly carcinogenic and mutagenic.
Organic ChemicalBiochemistryAMW:CHEM:020619
1-Naphthylisothiocyanate
A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronica…
Organic ChemicalBiochemistryAMW:CHEM:021524
1-Octanol
A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and…
Organic ChemicalBiochemistryAMW:CHEM:020113
1-Phosphatidylinositol 4-Kinase
An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphatidylinositol 4-phosphate, the first committed step…
Enzyme or CoenzymeBiochemistryAMW:CHEM:081543
1-Propanol
A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Organic ChemicalBiochemistryAMW:CHEM:020147
1-Pyrroline-5-Carboxylate Dehydrogenase
An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence of NAD. Defects in the enzyme are the cause of hyp…
Enzyme or CoenzymeBiochemistryAMW:CHEM:081148
1-Sarcosine-8-Isoleucine Angiotensin II
An ANGIOTENSIN II analog which acts as a highly specific inhibitor of ANGIOTENSIN TYPE 1 RECEPTOR.
Peptide or ProteinBiochemistryAMW:CHEM:120555
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt
A colorimetric reagent for iron, manganese, titanium, molybdenum, and complexes of zirconium. (From Merck Index, 11th ed)
Organic ChemicalBiochemistryAMW:CHEM:021307
1,2-Dimethylhydrazine
A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Organic ChemicalBiochemistryAMW:CHEM:021150
1,2-Dipalmitoylphosphatidylcholine
Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.
LipidBiochemistryAMW:CHEM:100169
1,4-alpha-Glucan Branching Enzyme
In glycogen or amylopectin synthesis, the enzyme that catalyzes the transfer of a segment of a 1,4-alpha-glucan chain to a primary hydroxy group in a…
Enzyme or CoenzymeBiochemistryAMW:CHEM:081370
11-beta-Hydroxysteroid Dehydrogenase Type 1
A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tissue; OVAR…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080994
11-beta-Hydroxysteroid Dehydrogenase Type 2
An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTIS…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080995
11-beta-Hydroxysteroid Dehydrogenases
Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can ut…
Enzyme or CoenzymeBiochemistryAMW:CHEM:080993
11-Hydroxycorticosteroids
A group of corticosteroids bearing a hydroxy group at the 11-position.
Hormonal AgentBiochemistryAMW:CHEM:060021
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue section…
LipidBiochemistryAMW:CHEM:100041
12E7 Antigen
A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-L…
CarbohydrateBiochemistryAMW:CHEM:090118
14-3-3 Proteins
A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding prot…
Peptide or ProteinBiochemistryAMW:CHEM:120337
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESS…
Inorganic ChemicalBiochemistryAMW:CHEM:010145