Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Adrenocorticotropic Hormone An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which … | Hormonal Agent | Biochemistry | Base domain | AMW:CHEM:060122 |
| Adrenodoxin An iron-sulfur protein which serves as an electron carrier in enzymatic steroid hydroxylation reactions in adrenal cortex mitochondria. The electron … | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120990 |
| Adrenomedullin A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed througho… | Hormonal Agent | Biochemistry | Base domain | AMW:CHEM:060073 |
| Advanced Oxidation Protein Products A class of dityrosine-containing protein-derived molecules formed by OXIDATIVE STRESS. Their accumulation in plasma is associated with certain pathol… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122472 |
| Aequorin A photoprotein isolated from the bioluminescent jellyfish Aequorea. It emits visible light by an intramolecular reaction when a trace amount of calci… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121814 |
| Aerogels A synthetic porous ultralight solid material is created from a gel through a supercritical drying process, in which the gel's liquid component is rep… | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200127 |
| Aerosolized Particles and Droplets A suspension of tiny particles or liquid droplets (< 5-10 microns) in the air. They sometimes cause adverse health effects when inhaled or absorbed. | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200003 |
| Aerosols Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may c… | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200122 |
| Afatinib A quinazoline and butenamide derivative that acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020215 |
| Aflatoxin B1 A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and cause… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030405 |
| Aflatoxin M1 A 4-hydroxylated metabolite of AFLATOXIN B1, one of the MYCOTOXINS from ASPERGILLUS tainted food. It is associated with LIVER damage and cancer resul… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030406 |
| Aflatoxins Furano-furano-benzopyrans that are produced by ASPERGILLUS from STERIGMATOCYSTIN. They are structurally related to COUMARINS and easily oxidized to a… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030404 |
| Agammaglobulinaemia Tyrosine Kinase A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc fing… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081693 |
| AGAMOUS Protein, Arabidopsis A plant homeotic protein involved in the development of stamens and carpels of Arabidopsis thaliana. It is a DNA-binding protein that contains the MA… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121534 |
| Agar A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090403 |
| Agatoxins A class of polyamine and peptide toxins which are isolated from the venom of spiders such as Agelenopsis aperta. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120669 |
| Agent Orange A herbicide that contains equal parts of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), as well as traces of… | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020772 |
| Aggrecans Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with th… | Carbohydrate | Biochemistry | Base domain | AMW:CHEM:090333 |
| Agmatine Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle. | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:020467 |
| Agouti Signaling Protein A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in MELANO… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120104 |
| Agouti-Related Protein A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR ac… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120105 |
| Agrin A protein component of the synaptic basal lamina. It has been shown to induce clustering of acetylcholine receptors on the surface of muscle fibers a… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122386 |
| AICDA (Activation-Induced Cytidine Deaminase) A CYTIDINE DEAMINASE required for several crucial steps of B Cell terminal differentiation. | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080300 |
| AIDS Vaccines Vaccines or candidate vaccines containing inactivated HIV or some of its component antigens and designed to prevent or treat AIDS. Some vaccines cont… | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200090 |
| Air Pollutants, Radioactive Pollutants present in air which exhibit radioactivity. | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200150 |
| AIRE Protein A transcriptional regulator primarily expressed in medullary thymic epithelial cells. It plays an important role in immunity by regulating the expres… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:122596 |
| Ajmaline An alkaloid found in the root of RAUWOLFIA SERPENTINA, among other plant sources. It is a class 1-A antiarrhythmic agent that apparently acts by chan… | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030096 |
| Alamethicin A cyclic nonadecapeptide antibiotic that can act as an ionophore and is produced by strains of Trichoderma viride. (From Singleton & Sainsbury, Dicti… | Polycyclic Compound | Biochemistry | Base domain | AMW:CHEM:040266 |
| Alanine A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in … | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120003 |
| Alanine Dehydrogenase An NAD-dependent enzyme that catalyzes the reversible DEAMINATION of L-ALANINE to PYRUVATE and AMMONIA. The enzyme is needed for growth when ALANINE … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:081156 |