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Browse canonical concepts by label, domain, node type, prefix and encoded class.

10,023 results

Concept	Node type	Base domain	Identifier
15-Oxoprostaglandin 13-Reductase (5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyze…	Enzyme or Coenzyme	Biochemistry	AMW:CHEM:081124
16,16-Dimethylprostaglandin E2 A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective e…	Lipid	Biochemistry	AMW:CHEM:100077
17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as a PROGESTIN and is used to reduce the risk of recurrent MISCARRIAGE and of PREMATURE BIRTH. It is also us…	Polycyclic Compound	Biochemistry	AMW:CHEM:040241
17-alpha-Hydroxypregnenolone A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis…	Polycyclic Compound	Biochemistry	AMW:CHEM:040245
17-alpha-Hydroxyprogesterone A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and G…	Polycyclic Compound	Biochemistry	AMW:CHEM:040240
17-Hydroxycorticosteroids A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal fun…	Hormonal Agent	Biochemistry	AMW:CHEM:060022
17-Hydroxysteroid Dehydrogenases A class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. EC 1.1.-.	Enzyme or Coenzyme	Biochemistry	AMW:CHEM:081000
17-Ketosteroids Steroids that contain a ketone group at position 17.	Polycyclic Compound	Biochemistry	AMW:CHEM:040143
18-Hydroxycorticosterone 11 beta,18,21-Trihydroxypregn-4-ene-3,20-dione.	Polycyclic Compound	Biochemistry	AMW:CHEM:040225
18-Hydroxydesoxycorticosterone An analog of desoxycorticosterone which is substituted by a hydroxyl group at the C-18 position.	Polycyclic Compound	Biochemistry	AMW:CHEM:040228
19-Iodocholesterol 19-Iodocholest-5-en-3 beta-ol. A cholesterol derivative usually substituted with radioactive iodine in the 19 position. The compound is an adrenal co…	Polycyclic Compound	Biochemistry	AMW:CHEM:040102
2-Acetolactate Mutase An enzyme involved in the biosynthesis of isoleucine and valine. It converts 2-acetolactate into 3-hydroxy-2-oxo-isovalerate. Also acts on 2-hydroxy-…	Enzyme or Coenzyme	Biochemistry	AMW:CHEM:080779
2-Acetylaminofluorene A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyf…	Organic Chemical	Biochemistry	AMW:CHEM:020200
2-Amino-5-phosphonovalerate The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA re…	Peptide or Protein	Biochemistry	AMW:CHEM:120035
2-Aminoadipate Transaminase A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-2-aminoadipate onto 2-oxoglutarate to generate 2-oxoadipate a…	Enzyme or Coenzyme	Biochemistry	AMW:CHEM:081415
2-Aminoadipic Acid A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-…	Organic Chemical	Biochemistry	AMW:CHEM:020864
2-Aminopurine A purine that is an isomer of ADENINE (6-aminopurine).	Heterocyclic Compound	Biochemistry	AMW:CHEM:030796
2-Chloroadenosine 2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the pe…	Heterocyclic Compound	Biochemistry	AMW:CHEM:030807
2-Hydroxy-5-nitrobenzyl Bromide A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and ot…	Organic Chemical	Biochemistry	AMW:CHEM:021323
2-Hydroxyphenethylamine Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also us…	Organic Chemical	Biochemistry	AMW:CHEM:020017
2-Hydroxypropyl-beta-cyclodextrin Derivative of beta-cyclodextrin that is used as an excipient for steroid drugs and as a lipid chelator.	Polycyclic Compound	Biochemistry	AMW:CHEM:040262
2-Isopropylmalate Synthase An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric aci…	Enzyme or Coenzyme	Biochemistry	AMW:CHEM:081323
2-Methoxyestradiol A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition …	Polycyclic Compound	Biochemistry	AMW:CHEM:040130
2-Methyl-4-chlorophenoxyacetic Acid A powerful herbicide used as a selective weed killer.	Organic Chemical	Biochemistry	AMW:CHEM:020774
2-Naphthylamine A naphthalene derivative with carcinogenic action.	Organic Chemical	Biochemistry	AMW:CHEM:020621
2-Oxoisovalerate Dehydrogenase (Acylating) An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE;…	Enzyme or Coenzyme	Biochemistry	AMW:CHEM:081103
2-Propanol An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as…	Organic Chemical	Biochemistry	AMW:CHEM:020148
2-Pyridinylmethylsulfinylbenzimidazoles Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGEN…	Organic Chemical	Biochemistry	AMW:CHEM:022024
2,2'-Dipyridyl A reagent used for the determination of iron.	Heterocyclic Compound	Biochemistry	AMW:CHEM:030502
2,3-Diketogulonic Acid Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID.	Organic Chemical	Biochemistry	AMW:CHEM:020916