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10,023 results

Current membership scope: Base domain only

ConceptNode typeBase domainMatched membershipIdentifier
Androstatrienes
Derivatives of the steroid androstane having three double bonds at any site in any of the rings.
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040025
Androstenediol
An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the r…
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040029
Androstenediols
Unsaturated androstane derivatives which are substituted with two hydroxy groups in any position in the ring system.
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040028
Androstenedione
A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstene…
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040026
Androstenes
Unsaturated derivatives of the steroid androstane containing at least one double bond at any site in any of the rings.
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040017
Androstenols
Unsaturated androstanes which are substituted with one or more hydroxyl groups in any position in the ring system.
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040027
Androsterone
A metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandroster…
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040007
Anethole Trithione
Choleretic used to allay dry mouth and constipation due to tranquilizers.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021126
Angiogenic Proteins
Intercellular signaling peptides and proteins that regulate the proliferation of new blood vessels under normal physiological conditions (ANGIOGENESI…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120106
Angiomotins
A class of intracellular signaling proteins that were originally identified as inhibitors of ANGIOSTATIN activity. They play a role in cell signaling…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120339
Angiopoietin-1
The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoi…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120116
Angiopoietin-2
An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of …
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120117
Angiopoietin-Like Protein 1
The first member of the Angiopoietin-like protein family to be discovered. It is considered a key endogenous ANTIANGIOGENIC AGENT which inhibits the …
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120108
Angiopoietin-Like Protein 2
A circulating angiopoietin-like protein that is expressed in a variety of tissues in response to HYPOXIA. It acts by inducing angiogenesis and endoth…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120109
Angiopoietin-Like Protein 3
An angiopoietin-like protein that plays a role in regulation of LIPOPROTEIN metabolism.
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120110
Angiopoietin-Like Protein 4
A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tub…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120111
Angiopoietin-Like Protein 6
An angiopoietin-like protein that is expressed in LIVER and involved in regulation of BLOOD GLUCOSE; LIPID METABOLISM; and ENERGY METABOLISM.
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120112
Angiopoietin-Like Protein 7
An angiopoietin-like protein that is expressed in NERVE TISSUE, KERATOCONUS corneas, TRABECULAR MESHWORK.
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120113
Angiopoietin-Like Protein 8
A nutritionally-regulated factor found in the LIVER. It plays a role in lipid metabolism and VLDL secretion in the liver. It was originally called be…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120114
Angiopoietin-like Proteins
A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-termina…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120107
Angiopoietins
A family of structurally related angiogenic proteins of approximately 70 kDa in size. They have high specificity for members of the TIE RECEPTOR FAMI…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120115
Angiostatic Proteins
Proteins that specifically inhibit the growth of new blood vessels (ANGIOGENESIS, PHYSIOLOGIC).
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120118
Angiostatins
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHI…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080090
Angiotensin Amide
The octapeptide amide of bovine angiotensin II used to increase blood pressure by vasoconstriction.
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120553
Angiotensin I
A decapeptide that is cleaved from precursor angiotensinogen by RENIN. Angiotensin I has limited biological activity. It is converted to angiotensin …
Hormonal AgentBiochemistryBase domainAMW:CHEM:060075
Angiotensin II
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal …
Hormonal AgentBiochemistryBase domainAMW:CHEM:060076
Angiotensin III
A heptapeptide formed from ANGIOTENSIN II after the removal of an amino acid at the N-terminal by AMINOPEPTIDASE A. Angiotensin III has the same effi…
Hormonal AgentBiochemistryBase domainAMW:CHEM:060077
Angiotensin-Converting Enzyme 2
A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue fro…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080700
Angiotensinogen
An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted …
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120556
Angiotensins
Oligopeptides which are important in the regulation of blood pressure (VASOCONSTRICTION) and fluid homeostasis via the RENIN-ANGIOTENSIN SYSTEM. Thes…
Hormonal AgentBiochemistryBase domainAMW:CHEM:060074