Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Base domain only
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| Antivenins Antisera used to counteract poisoning by animal VENOMS, especially SNAKE VENOMS. | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120866 |
| Antiviral Restriction Factors A broad category of endogenous host cellular factors upregulated in response to pathogens (i.e., INTERFERON-stimulated genes) and recruited to interf… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120655 |
| Apamin A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes… | Complex Mixture | Biochemistry | Base domain | AMW:CHEM:200175 |
| Apatites A group of phosphate minerals that includes ten mineral species and has the general formula X5(YO4)3Z, where X is usually calcium or lead, Y is phosp… | Inorganic Chemical | Biochemistry | Base domain | AMW:CHEM:010025 |
| Apazone An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030664 |
| Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080844 |
| Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080845 |
| Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain wh… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080846 |
| Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin do… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080847 |
| Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. Thes… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080848 |
| Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modul… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080849 |
| Apc5 Subunit, Anaphase-Promoting Complex-Cyclosome A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modul… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080850 |
| Apc6 Subunit, Anaphase-Promoting Complex-Cyclosome A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080851 |
| Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080852 |
| Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080853 |
| Apelin A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120127 |
| Apelin Receptors G-protein coupled receptors for APELIN that function in a broad range of physiologic processes including blood pressure regulation and heart contract… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:121927 |
| Aphidicolin An antiviral antibiotic produced by Cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses … | Organic Chemical | Biochemistry | Base domain | AMW:CHEM:021621 |
| Apigenin 5,7,4'-trihydroxy-flavone, one of the FLAVONES. | Heterocyclic Compound | Biochemistry | Base domain | AMW:CHEM:030420 |
| APOBEC Deaminases A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-depen… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080301 |
| APOBEC-1 Deaminase An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post-transcripti… | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080302 |
| APOBEC-3G Deaminase An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080303 |
| Apoenzymes The protein components of enzyme complexes (HOLOENZYMES). An apoenzyme is the holoenzyme minus any cofactors (ENZYME COFACTORS) or prosthetic groups … | Enzyme or Coenzyme | Biochemistry | Base domain | AMW:CHEM:080138 |
| Apoferritins The protein components of ferritins. Apoferritins are shell-like structures containing nanocavities and ferroxidase activities. Apoferritin shells ar… | Peptide or Protein | Biochemistry | Base domain | AMW:CHEM:120658 |
| Apolipoprotein A-I The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus … | Lipid | Biochemistry | Base domain | AMW:CHEM:100133 |
| Apolipoprotein A-II The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN … | Lipid | Biochemistry | Base domain | AMW:CHEM:100134 |
| Apolipoprotein A-V A minor apolipoprotein that associates with HIGH-DENSITY LIPOPROTEINS (HDL), VERY-LOW-DENSITY LIPOPROTEINS (VLDL), and CHYLOMICRONS. It regulates lev… | Lipid | Biochemistry | Base domain | AMW:CHEM:100135 |
| Apolipoprotein B-100 A 513-kDa protein synthesized in the LIVER. It serves as the major structural protein of low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, V… | Lipid | Biochemistry | Base domain | AMW:CHEM:100138 |
| Apolipoprotein B-48 A 241-kDa protein synthesized only in the INTESTINES. It serves as a structural protein of CHYLOMICRONS. Its exclusive association with chylomicron p… | Lipid | Biochemistry | Base domain | AMW:CHEM:100137 |
| Apolipoprotein C-I A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO… | Lipid | Biochemistry | Base domain | AMW:CHEM:100140 |