Nodes

A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primaril…

Diaza derivative of cholesterol which acts as a hypocholesteremic agent by blocking delta-24-reductase, which causes the accumulation of desmosterol.

One of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.

A butyrophenone used in the treatment of PSYCHOSES.

Antibiotic substance produced by various Streptomyces species. It is an inhibitor of enzymatic activities that involve glutamine and is used as an an…

Steroidal compounds in which one or more carbon atoms in the steroid ring system have been substituted with nitrogen atoms.

An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to th…

A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular n…

Seven membered heterocyclic rings containing a NITROGEN atom.

A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological activit…

Azetidines is an imported chemical/drug node from the registry.

Azetines is an imported chemical/drug node from the registry.

Organic or inorganic compounds that contain the -N3 group.

An organothiophosphorus cholinesterase inhibitor. It has been used as an acaricide and as an insecticide.

Saturated azacyclopropane compounds. They include compounds with substitutions on CARBON or NITROGEN atoms.

Unsaturated azacyclopropane compounds that are three-membered heterocycles of a nitrogen and two carbon atoms.

A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare i…

A semisynthetic ampicillin-derived acylureido penicillin.

Organic chemicals where aryl or alkyl groups are joined by two nitrogen atoms through a double bond (R-N=N-R'; R and R' may be either aryl or alkyl).…

Azocines is an imported chemical/drug node from the registry.

Five membered rings containing a NITROGEN atom.

A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas.

A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negati…

Compounds based on a seven-membered ring fused to a five-membered ring. Heat can rearrange them to NAPHTHALENES which have two fused six-membered rin…

PHENOTHIAZINES with an amino group at the 3-position that are green crystals or powder. They are used as biological stains.

A bacterial protein from Pseudomonas, Bordetella, or Alcaligenes which operates as an electron transfer unit associated with the cytochrome chain. Th…

A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that i…

A member of the tumor necrosis factor receptor superfamily that specifically binds B-CELL ACTIVATING FACTOR. It is found on B-LYMPHOCYTES and plays a…

A signal transducing adaptor protein that contains an N-terminal CARD DOMAIN and functions in the ADAPTIVE IMMUNE RESPONSE. It promotes PRO-CASPASE-9…

A member of the I kappa B family, B-cell lymphoma 3-encoded (bcl-3) protein is involved in the regulation of TRANSCRIPTIONAL ACTIVATION of NF-KAPPA B…