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Browse canonical concepts by label, domain, node type, prefix and encoded class.

10,023 results

Current membership scope: Base domain only

ConceptNode typeBase domainMatched membershipIdentifier
Bone Morphogenetic Protein Receptors, Type I
A subtype of bone morphogenetic protein receptors with high affinity for BONE MORPHOGENETIC PROTEINS. They can interact with and undergo PHOSPHORYLAT…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:081561
Bone Morphogenetic Protein Receptors, Type II
A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS. They are constitutively active PROTEIN SERINE-TH…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:081562
Bone Morphogenetic Proteins
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precurs…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120313
Bone Substitutes
Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapat…
MaterialBiochemistryBase domainAMW:CHEM:250003
Bongkrekic Acid
An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleo…
Organic ChemicalBiochemistryBase domainAMW:CHEM:020866
Boranes
The collective name for the boron hydrides, which are analogous to the alkanes and silanes. Numerous boranes are known. Some have high calorific valu…
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010080
Borates
Inorganic or organic salts and esters of boric acid.
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010083
Boric Acids
Inorganic and organic derivatives of boric acid either B(OH)3 or, preferably H3BO3.
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010004
Borinic Acids
Inorganic or organic compounds that contain the general structure R2B(OH).
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010005
Borohydrides
A class of inorganic or organic compounds that contain the borohydride (BH4-) anion.
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010081
Boron
A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron ab…
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010224
Boron Compounds
Inorganic or organic compounds that contain boron as an integral part of the molecule.
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010079
Boronic Acids
Inorganic or organic compounds that contain the basic structure RB(OH)2.
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010006
Bortezomib
A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of…
Inorganic ChemicalBiochemistryBase domainAMW:CHEM:010007
Bosentan
A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROS…
Organic ChemicalBiochemistryBase domainAMW:CHEM:020368
Bothrops jararaca Venom
Snake venoms isolated from BOTHROPS JARARACA. B. jararaca venoms contain a hemorrhagic metalloproteinase toxn jararhagin which binds to VON WILLEBRAN…
Complex MixtureBiochemistryBase domainAMW:CHEM:200190
Botulinum Antitoxin
Antiserum given therapeutically in BOTULISM.
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120867
Botulinum Toxins
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature…
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080609
Botulinum Toxins, Type A
A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.
Enzyme or CoenzymeBiochemistryBase domainAMW:CHEM:080610
Brachyury Protein
A T-box transcription factor which regulates the expression of genes required for MESODERM formation and differentiation.
Peptide or ProteinBiochemistryBase domainAMW:CHEM:121639
Bradykinin
A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation a…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120271
Brain-Derived Neurotrophic Factor
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neuro…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120288
Brassinosteroids
Plant steroids ubiquitously distributed throughout the plant kingdom. They play essential roles in modulating growth and differentiation of cells at …
Polycyclic CompoundBiochemistryBase domainAMW:CHEM:040120
BRCA1 Protein
The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory su…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:121706
BRCA2 Protein
A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 p…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:121707
Brefeldin A
A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity.
Organic ChemicalBiochemistryBase domainAMW:CHEM:021760
Brentuximab Vedotin
Immunoconjugate that consists of the chimeric monoclonal anti - CD30 ANTIGEN antibody cAC-10 conjugated to monomethyl auristatin E. It is used for th…
Peptide or ProteinBiochemistryBase domainAMW:CHEM:120558
Bretylium Compounds
Benzylammonium compounds with the formula Br-phenyl-CN+R3 that include BRETYLIUM TOSYLATE.
Organic ChemicalBiochemistryBase domainAMW:CHEM:020654
Bretylium Tosylate
An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now…
Organic ChemicalBiochemistryBase domainAMW:CHEM:020655
Brevican
A BRAIN-specific hyalectin that may play a role in terminally differentiating NEURONS. It is found highly overexpressed in primary BRAIN TUMORS and i…
CarbohydrateBiochemistryBase domainAMW:CHEM:090334