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ConceptNode typeBase domainMatched membershipIdentifier
Fetofetal Transfusion
Passage of blood from one fetus to another via an arteriovenous communication or other shunt, in a monozygotic twin pregnancy. It results in anemia i…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150034
Fetomaternal Transfusion
Transplacental passage of fetal blood into the circulation of the maternal organism. (Dorland, 27th ed)
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150035
GATA2 Deficiency
A rare disorder of the immune system with wide-ranging effects which include GATA2 Transcription Factor dysfunction, immunodeficiency, myelodysplasti…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150102
Glucosephosphate Dehydrogenase Deficiency
A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in ery…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150018
Granuloma
A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
Pathologic ConditionPathologyHematopoietic System [curated_secondary]AMW:DIS:150156
Granulomatous Disease, Chronic
A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granulo…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150127
Gray Platelet Syndrome
A rare, inherited platelet disorder characterized by a selective deficiency in the number and contents of platelet alpha-granules. It is associated w…
SyndromePathologyHematopoietic System [curated_secondary]AMW:DIS:150076
Heavy Chain Disease
A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the …
Immune DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150095
Hematologic Diseases
Disorders of the blood and blood forming tissues.
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150002
Hemic and Lymphatic Diseases
Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed elements (e.g., ERYTHRO…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150001
Hemoglobin C Disease
A disease characterized by compensated hemolysis with a normal hemoglobin level or a mild to moderate anemia. There may be intermittent abdominal dis…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150020
Hemoglobin SC Disease
One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle c…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150014
Hemoglobinopathies
A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150116
Hemoglobinuria, Paroxysmal
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal co…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150026
Hemophilia A
The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tend…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150052
Hemophilia B
A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in d…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150053
Hemorrhagic Disorders
Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (BLOOD COAGULATION DISORDERS) or another abnormality causing a str…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150117
Histiocytic Necrotizing Lymphadenitis
Development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes …
Inflammatory DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150142
Histiocytosis
General term for the abnormal appearance of histiocytes in the blood. Based on the pathological features of the cells involved rather than on clinica…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150135
Histiocytosis, Non-Langerhans-Cell
Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group i…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150136
Histiocytosis, Sinus
Benign, non-Langerhans-cell, histiocytic proliferative disorder that primarily affects the lymph nodes. It is often referred to as sinus histiocytosi…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150138
Hyper-IgM Immunodeficiency Syndrome
A rare inherited immunodeficiency syndrome characterized by normal or elevated serum IMMUNOGLOBULIN M levels with absence of IMMUNOGLOBULIN G; IMMUNO…
SyndromePathologyHematopoietic System [curated_secondary]AMW:DIS:150086
Hyper-IgM Immunodeficiency Syndrome, Type 1
An X-linked hyper-IgM immunodeficiency subtype resulting from mutation in the gene encoding CD40 LIGAND.
SyndromePathologyHematopoietic System [curated_secondary]AMW:DIS:150087
Hypereosinophilic Syndrome
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, includ…
SyndromePathologyHematopoietic System [curated_secondary]AMW:DIS:150121
Hypergammaglobulinemia
An excess of GAMMA-GLOBULINS in the serum due to chronic infections or PARAPROTEINEMIAS.
Immune DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150090
Hypersplenism
Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marr…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150163
Hypoalbuminemia
A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthe…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150093
Hypoproteinemia
A condition in which total serum protein level is below the normal range. Hypoproteinemia can be caused by protein malabsorption in the gastrointesti…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150092
Hypoprothrombinemias
Absence or reduced levels of PROTHROMBIN in the blood.
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150054
IgA Deficiency
A dysgammaglobulinemia characterized by a deficiency of IMMUNOGLOBULIN A.
Immune DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150088