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167 results

Current membership scope: Domain and all descendants

ConceptNode typeBase domainMatched membershipIdentifier
Non-Filarial Lymphedema
A form of elephantiasis caused by soil particles which penetrate the skin of the foot. It is limited to tropical regions with soils of high volcanic …
Pathologic ConditionPathologyHematopoietic System [curated_secondary]AMW:DIS:150152
Pancytopenia
Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150115
Paraproteinemias
A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single…
Immune DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150094
Pelger-Huet Anomaly
Autosomal dominant anomaly characterized by abnormal ovoid shape GRANULOCYTE nuclei and their clumping chromatin. Mutations in the LAMIN B receptor g…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150125
Phagocyte Bactericidal Dysfunction
Disorders in which phagocytic cells cannot kill ingested bacteria; characterized by frequent recurring infection with formulation of granulomas.
Functional DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150126
Platelet Storage Pool Deficiency
Disorder characterized by a decrease or lack of platelet dense bodies in which the releasable pool of adenine nucleotides and 5HT are normally stored.
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150065
Polycythemia
An increase in the total red cell mass of the blood. (Dorland, 27th ed)
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150130
Primary Myelofibrosis
A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process t…
Pathologic ConditionPathologyHematopoietic System [curated_secondary]AMW:DIS:150106
Protein C Deficiency
An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or p…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150055
Protein S Deficiency
An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embo…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150066
Pseudolymphoma
A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. Pseudolymphoma is cha…
Neoplastic DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150161
Pseudothrombocytopenia
A laboratory phenomenon where a low platelet count is observed due to the action of ANTICOAGULANTS such as EDTA causing platelet AGGLUTINATION.
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150079
Purpura
Purplish or brownish red discoloration, easily visible through the epidermis, caused by hemorrhage into the tissues. When the size of the discoloriza…
Pathologic ConditionPathologyHematopoietic System [curated_secondary]AMW:DIS:150067
Purpura Fulminans
A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading…
Pathologic ConditionPathologyHematopoietic System [curated_secondary]AMW:DIS:150068
Purpura, Thrombocytopenic
Any form of purpura in which the PLATELET COUNT is decreased. Many forms are thought to be caused by immunological mechanisms.
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150069
Purpura, Thrombocytopenic, Idiopathic
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in…
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150070
Purpura, Thrombotic Thrombocytopenic
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical feature…
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150071
Red-Cell Aplasia, Pure
Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production.
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150039
Sarcoidosis
An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually i…
Immune DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150158
Sickle Cell Trait
The condition of being heterozygous for hemoglobin S.
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150015
Spherocytosis, Hereditary
A group of familial congenital hemolytic anemias characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. The erythro…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150021
Splenic Diseases
Diseases involving the SPLEEN.
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150162
Splenic Rupture
Rupture of the SPLEEN due to trauma or disease.
Traumatic DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150164
Splenosis
The spontaneous transplantation of splenic tissue to unusual sites after open splenic trauma, e.g., after automobile accidents, gunshot or stab wound…
Traumatic DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150165
Sulfhemoglobinemia
A morbid condition due to the presence of sulfmethemoglobin in the blood. It is marked by persistent cyanosis, but the blood count does not reveal an…
DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150131
T-Lymphocytopenia, Idiopathic CD4-Positive
Reproducible depletion of CD4+ lymphocytes below 300 per cubic millimeter in the absence of HIV infection or other known causes of immunodeficiency. …
Immune DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150114
Thalassemia
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic…
Congenital DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150022
Thrombasthenia
A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impa…
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150056
Thrombocythemia, Essential
A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150072
Thrombocytopenia
A subnormal level of BLOOD PLATELETS.
Vascular DisorderPathologyHematopoietic System [curated_secondary]AMW:DIS:150077