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Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such…

A circumscribed melanosis consisting of a brown-pigmented, velvety verrucosity or fine papillomatosis appearing in the axillae and other body folds. …

Severe and chronic form of acne characterized by large, burrowing abscesses associated with disfigurement.

A type of acneiform disorder in which secondary pyogenic infection in and around pilosebaceous structures ends in keloidal scarring. It manifests as …

A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads),…

Visible efflorescent lesions of the skin caused by acne or resembling acne. (Dorland, 28th ed, p18, 575)

Inflammation involving the skin of the extremities, especially the hands and feet. Several forms are known, some idiopathic and some hereditary. The …

Rare skin eruption characterized by acute formation of pustules filled with NEUTROPHILS, fever, and peripheral blood LEUKOCYTOSIS. Most cases are ass…

A rare disease characterized by multiple tumor-like fatty deposits that press on nerves in various sites causing pain and weakness. Often these lipom…

Absence of hair from areas where it is normally present.

Loss of scalp and body hair involving microscopically inflammatory patchy areas.

Benign DERMATOSIS caused by a loss of dermal ELASTIC TISSUE resulting in localized sac-like areas of flaccid skin. It can be either primary (idiopath…

A permanent ashen-gray discoloration of the skin, conjunctiva, and internal organs resulting from long-continued use of silver salts. (Dorland, 27th …

Visible accumulations of fluid within or beneath the epidermis.

Light brown pigmented macules associated with NEUROFIBROMATOSIS and Albright's syndrome (see FIBROUS DYSPLASIA, POLYOSTOTIC).

Pathological deposition of calcium in the skin and subcutaneous tissue. Excessive calcification of the skin may be associated with underlying disease…

Localized hyperplasia of the horny layer of the epidermis due to pressure or friction. (Dorland, 27th ed)

Skin lumpiness or skin surface dimpling often seen on the thighs, buttocks and abdomen. It is due to protrusion of SUBCUTANEOUS FAT into the DERMIS l…

Cellulitis of upper limb used as a ClinicalGraph target concept for pathology / differential.

ACNE-like skin eruptions caused by exposure to CHLORINE-containing compounds. Exposure can be by inhalation, ingestion, or through the skin. Chloracn…

Chronic urticaria with identified triggering factor which is either physical, e.g., vibratory urticaria, or non-physical, e.g., aquagenic urticaria.

Wheals (urticaria) and/or angioedema presented with daily symptoms lasting for more than 6 weeks. It may be classified into chronic spontaneous and c…

Various skin flares developing after exposure to cold temperature. While most are characterized by a limited episodic cutaneous condition characteriz…

An abnormal passage or communication leading from an internal organ to the surface of the body.

A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue for…

Excessive shedding of dry scaly material from the scalp in humans.

An autosomal dominantly inherited skin disorder characterized by warty malodorous papules that coalesce into plaques. It is caused by mutations in th…

Any inflammation of the skin.

Rare, chronic, papulo-vesicular disease characterized by an intensely pruritic eruption consisting of various combinations of symmetrical, erythemato…

A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of…