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Test to measure the levels of NITRIC OXIDE (an ENDOTHELIUM-DEPENDENT RELAXING FACTOR) in the exhaled air. FeNO test is used to determine levels of in…

A method which uses specific precipitation reactions to separate or collect substances from a solution.

Separation of molecules and particles by a simultaneous action of carrier liquid flow and focusing field forces (electrical, sedimentation, or therma…

Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used…

A replica technique in which cells are frozen to a very low temperature and cracked with a knife blade to expose the interior surfaces of the cells o…

Preparation for electron microscopy of minute replicas of exposed surfaces of the cell which have been ruptured in the frozen state. The specimen is …

A modification of the freeze-drying method in which the ice within the frozen tissue is replaced by alcohol or other solvent at a very low temperatur…

Thinly cut sections of frozen tissue specimens prepared with a cryostat or freezing microtome.

A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compound…

Gastric analysis for determination of free acid or total acid.

Medical procedure involving the emptying of contents in the stomach through the use of a tube inserted through the nose or mouth. It is performed to …

The techniques involved in creating and inserting synthetic selfish genetic elements called gene drives. Gene drives carry a payload gene and are des…

Genetic engineering or molecular biology techniques that involve DNA REPAIR mechanisms for incorporating site-specific modifications into a cell's ge…

The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.

Techniques used to add in exogenous gene sequence such as mutated genes; REPORTER GENES, to study mechanisms of gene expression; or regulatory contro…

The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-…

Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during dev…

The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as …

The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene tra…

The analysis of a sequence such as a region of a chromosome, a haplotype, a gene, or an allele for its involvement in controlling the phenotype of a …

Identification of individuals who are heterozygous at a GENETIC LOCUS for a recessive PHENOTYPE.

A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype wh…

Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a…

The use of genetic methodologies to improve functional capacities of an organism rather than to treat disease.

The transfer of genetic material from one species to another by inter-species hybridization and repeated backcrossing.

Estimate of an individual's genetic liability to a trait or disease, calculated according to their genotype profile and relevant genome-wide associat…

Chromosomal, biochemical, intracellular, and other methods used in the study of genetics.

Detection of a MUTATION; GENOTYPE; KARYOTYPE; or specific ALLELES associated with genetic traits, heritable diseases, or predisposition to a disease,…

An analysis comparing the allele frequencies of all available (or a whole GENOME representative set of) polymorphic markers to identify gene candidat…

Methods used to determine individuals' specific ALLELES or SNPS (single nucleotide polymorphisms).