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ConceptNode typeBase domainMatched membershipIdentifier
Muscle Hypertonia
Abnormal increase in skeletal or smooth muscle tone. Skeletal muscle hypertonicity may be associated with PYRAMIDAL TRACT lesions or BASAL GANGLIA DI…
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100523
Muscle Hypotonia
A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100524
Muscular Atrophy
Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessnes…
Degenerative DisorderPathologyNervous System [curated_secondary]AMW:DIS:100525
Muscular Atrophy, Spinal
A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually witho…
Degenerative DisorderPathologyNervous System [curated_secondary]AMW:DIS:100319
Myasthenia Gravis, Autoimmune, Experimental
Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AC…
Immune DisorderPathologyNervous System [curated_secondary]AMW:DIS:100013
Myasthenia Gravis, Neonatal
A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually pr…
Congenital DisorderPathologyNervous System [curated_secondary]AMW:DIS:100014
Myasthenic Syndromes, Congenital
A heterogeneous group of disorders characterized by a congenital defect in neuromuscular transmission at the NEUROMUSCULAR JUNCTION. This includes pr…
SyndromePathologyNervous System [curated_secondary]AMW:DIS:100578
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease
A disease in which serum antibodies are directed against MYELIN-OLIGODENDROCYTE GLYCOPROTEIN. MOGAD is typically associated with ACUTE DISSEMINATED E…
DisorderPathologyNervous System [curated_secondary]AMW:DIS:100011
Myelinolysis, Central Pontine
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alteration…
Metabolic DisorderPathologyNervous System [curated_secondary]AMW:DIS:100132
Myoclonic Cerebellar Dyssynergia
A condition marked by progressive CEREBELLAR ATAXIA combined with MYOCLONUS usually presenting in the third decade of life or later. Additional clini…
Congenital DisorderPathologyNervous System [curated_secondary]AMW:DIS:100161
Myoclonic Epilepsies, Progressive
A heterogeneous group of primarily familial EPILEPSY disorders characterized by myoclonic seizures, tonic-clonic seizures, ataxia, progressive intell…
DisorderPathologyNervous System [curated_secondary]AMW:DIS:100251
Myoclonic Epilepsy, Juvenile
A disorder characterized by the onset of myoclonus in adolescence, a marked increase in the incidence of absence seizures (see EPILEPSY, ABSENCE), an…
DisorderPathologyNervous System [curated_secondary]AMW:DIS:100254
Myoclonus
Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may…
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100442
Myokymia
Successive and rapid contractions of motor units associated with chronic nerve injury. The discharges arise from the peripheral aspects of regenerati…
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100527
Myotonia
Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation o…
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100528
Narcolepsy
A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automati…
DisorderPathologyNervous System [curated_secondary]AMW:DIS:100637
Neonatal Brachial Plexus Palsy
Perinatal nerve injury involving the BRACHIAL PLEXUS involving a weak or paralyzed upper extremity.
Congenital DisorderPathologyNervous System [curated_secondary]AMW:DIS:100584
Nerve Compression Syndromes
Mechanical compression of nerves or nerve roots from internal or external causes. These may result in a conduction block to nerve impulses (due to MY…
SyndromePathologyNervous System [curated_secondary]AMW:DIS:100601
Nervous System Autoimmune Disease, Experimental
Experimental animal models for human AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM. They include GUILLAIN-BARRE SYNDROME (see NEURITIS, AUTOIMMUNE, EXPER…
Immune DisorderPathologyNervous System [curated_secondary]AMW:DIS:100015
Nervous System Diseases
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve ro…
DisorderPathologyNervous System [curated_secondary]AMW:DIS:100001
Nervous System Malformations
Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis.
Congenital DisorderPathologyNervous System [curated_secondary]AMW:DIS:100375
Neural Tube Defects
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of…
Congenital DisorderPathologyNervous System [curated_secondary]AMW:DIS:100401
Neuralgia
Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100606
Neuralgia, Postherpetic
Pain in nerves, frequently involving facial SKIN, resulting from the activation the latent varicella-zoster virus (HERPESVIRUS 3, HUMAN). The two for…
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100607
Neuritis
A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHES…
Inflammatory DisorderPathologyNervous System [curated_secondary]AMW:DIS:100608
Neuritis, Autoimmune, Experimental
An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected wi…
Immune DisorderPathologyNervous System [curated_secondary]AMW:DIS:100017
Neuroacanthocytosis
An inherited autosomal disorder that is characterized by neurodegeneration; orofacial and buccal DYSKINESIAS; CHOREA; and thorny-looking red cells (A…
Congenital DisorderPathologyNervous System [curated_secondary]AMW:DIS:100310
Neuroaxonal Dystrophies
A nonspecific term referring both to the pathologic finding of swelling of distal portions of axons in the brain and to disorders which feature this …
DisorderPathologyNervous System [curated_secondary]AMW:DIS:100300
Neurobehavioral Manifestations
Signs and symptoms of higher cortical dysfunction caused by organic conditions. These include certain behavioral alterations and impairments of skill…
Pathologic ConditionPathologyNervous System [curated_secondary]AMW:DIS:100450
Neurocutaneous Syndromes
A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.
SyndromePathologyNervous System [curated_secondary]AMW:DIS:100412