Public registry
Nodes
Browse canonical concepts by label, domain, node type, prefix and encoded class.
Current membership scope: Domain and all descendants
| Concept | Node type | Base domain | Matched membership | Identifier |
|---|---|---|---|---|
| CREST Syndrome A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORD… | Syndrome | Pathology | Digestive System [curated_secondary] | AMW:DIS:060053 |
| Cri-du-Chat Syndrome An infantile syndrome characterized by a cat-like cry, failure to thrive, microcephaly, MENTAL RETARDATION, spastic quadriparesis, micro- and retrogn… | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100486 |
| Crisscross Heart A developmental malformation of the heart characterized by a twisted but not defective atrioventicular connection. The abnormal rotation of the ventr… | Congenital Disorder | Pathology | Cardiovascular System [curated_secondary] | AMW:DIS:140014 |
| Crohn Disease A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the … | Disorder | Pathology | Digestive System [curated_secondary] | AMW:DIS:060099 |
| Cronkhite-Canada Syndrome A nonfamilial polyposis syndrome that is characterized by the presence of diffuse gastrointestinal polyposis, skin hyperpigmentation, ALOPECIA; DIARR… | Syndrome | Pathology | Digestive System [curated_secondary] | AMW:DIS:060139 |
| Croup Inflammation involving the GLOTTIS or VOCAL CORDS and the subglottic larynx. Croup is characterized by a barking cough, HOARSENESS, and persistent in… | Disorder | Pathology | Respiratory System [curated_secondary] | AMW:DIS:080027 |
| Crushing Retrosternal Chest Pain Created as a target node for a staged ClinicalGraph edge. Review and enrich this node later if needed. | Symptom | Clinical Medicine | Respiratory System [role_derived] | AMW:SYM:105037 |
| Cryoglobulinemia A condition characterized by the presence of abnormal quantities of CRYOGLOBULINS in the blood. Upon cold exposure, these abnormal proteins precipita… | Immune Disorder | Pathology | Cardiovascular System [curated_secondary] | AMW:DIS:140257 |
| Cryptogenic Organizing Pneumonia An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a pneumonia-like i… | Disorder | Pathology | Respiratory System [curated_secondary] | AMW:DIS:080018 |
| Cryptorchidism A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent i… | Congenital Disorder | Pathology | Reproductive System [curated_secondary] | AMW:DIS:120302 |
| Crystal Arthropathies Joint disorders that are characterized by accumulation of microcrystals in and around the joint including in the SYNOVIAL FLUID. They are classified … | Disorder | Pathology | Musculoskeletal System [curated_secondary] | AMW:DIS:050218 |
| Crystalluria Primarily a pathological, laboratory or structured observational finding rather than a disease entity. | Laboratory Finding | Laboratory Medicine | Renal and Urinary System [curated_secondary] | AMW:FIND:140029 |
| Cubital Tunnel Syndrome Compression of the ULNAR NERVE in the cubital tunnel, which is formed by the two heads of the flexor carpi ulnaris muscle, humeral-ulnar aponeurosis,… | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100599 |
| Cushing Syndrome A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources.… | Syndrome | Pathology | Endocrine System [curated_secondary] | AMW:DIS:190009 |
| Cutaneous Fistula An abnormal passage or communication leading from an internal organ to the surface of the body. | Pathologic Condition | Pathology | Integumentary System [curated_secondary] | AMW:DIS:170037 |
| Cutis Laxa A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue for… | Congenital Disorder | Pathology | Integumentary System [curated_secondary] | AMW:DIS:160143 |
| Cyanosis Primarily an observable or examinable clinical manifestation rather than a disease entity. | Clinical Sign | Clinical Medicine | Cardiovascular System [curated_secondary] | AMW:SIGN:115025 |
| Cyclodialysis Clefts Finding of a separation of the CILIARY BODY in the SCLERAL SPUR region, creating aqueous outflow from the ANTERIOR CHAMBER into suprachoroidal space … | Disorder | Pathology | Visual System [curated_secondary] | AMW:DIS:110031 |
| Cystic Adenomatoid Malformation of Lung, Congenital An abnormality in lung development that is characterized by a multicystic mass resulting from an adenomatous overgrowth of the terminal BRONCHIOLES w… | Neoplastic Disorder | Pathology | Respiratory System [curated_secondary] | AMW:DIS:080039 |
| Cystic Fibrosis The label is process-shaped, but the organ-specific concept may also function as a disorder; manual semantic review is required. | Pathological process | Pathology | Digestive System [curated_secondary] | AMW:PROC:155020 |
| Cystinuria An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria … | Congenital Disorder | Pathology | Renal and Urinary System [curated_secondary] | AMW:DIS:120154 |
| Cystitis Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), … | Inflammatory Disorder | Pathology | Renal and Urinary System [role_derived] | AMW:DIS:120170 |
| Cystitis, Hemorrhagic A diffuse inflammation of the URINARY BLADDER characterized by HEMATURIA due to bleeding from the bladder mucosa. Hemorrhagic cystitis is most often … | Inflammatory Disorder | Pathology | Renal and Urinary System [curated_secondary] | AMW:DIS:120171 |
| Cystitis, Interstitial A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of p… | Inflammatory Disorder | Pathology | Renal and Urinary System [curated_secondary] | AMW:DIS:120172 |
| Cystocele A HERNIA-like condition in which the weakened pelvic muscles cause the URINARY BLADDER to drop from its normal position. Fallen urinary bladder is mo… | Pathologic Condition | Pathology | Reproductive System [curated_secondary] | AMW:DIS:120173 |
| Cytopenia A deficiency in or reduction of the number of blood cells. | Disorder | Pathology | Hematopoietic System [curated_secondary] | AMW:DIS:150107 |
| Dacryocystitis Inflammation of the lacrimal sac. (Dorland, 27th ed) | Inflammatory Disorder | Pathology | Visual System [curated_secondary] | AMW:DIS:110075 |
| Dandruff Excessive shedding of dry scaly material from the scalp in humans. | Disorder | Pathology | Integumentary System [curated_secondary] | AMW:DIS:170039 |
| Dandy-Walker Syndrome A congenital abnormality of the central nervous system marked by failure of the midline structures of the cerebellum to develop, dilation of the four… | Syndrome | Pathology | Nervous System [curated_secondary] | AMW:DIS:100158 |
| Darier Disease An autosomal dominantly inherited skin disorder characterized by warty malodorous papules that coalesce into plaques. It is caused by mutations in th… | Congenital Disorder | Pathology | Integumentary System [curated_secondary] | AMW:DIS:160144 |