Organic Chemical

Sirolimus

AMW:CHEM:021751

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

Biochemistry chemical

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Graph assertions

Sirolimus has parent Macrolides

Everolimus has parent Sirolimus

Sirolimus member of drug class Immunosuppressant-Cytotoxic Drugs

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Identifier classification

PrefixChemical substances · AMW:CHEM:

Class02 · Organic Chemicals

Domains

Biochemistry · base Pharmacology · base

Semantic roles

Biochemistry / Concept Pharmacology / Drug

Public labels

Sirolimus en · preferred