Heterocyclic Compound

Leflunomide

AMW:CHEM:030230

An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.

Biochemistry chemical

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Graph assertions

Leflunomide has parent Isoxazoles

Leflunomide member of drug class Disease Modifying Antirheumatic Drugs

Leflunomide member of drug class Immunosuppressants- Antirheumatic Drugs

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Identifier classification

PrefixChemical substances · AMW:CHEM:

Class03 · Heterocyclic Compounds

Domains

Biochemistry · base Pharmacology · base

Semantic roles

Biochemistry / Concept Pharmacology / Drug

Public labels

Leflunomide en · preferred