Enzyme or Coenzyme

PTEN Phosphohydrolase

AMW:CHEM:080454

A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION.

Biochemistry biochemical

Read knowledge page ↗ Open graph Embed card

Graph assertions

PTEN Phosphohydrolase has parent Intracellular Signaling Peptides and Proteins

PTEN Phosphohydrolase has parent Phosphoric Monoester Hydrolases

PTEN Phosphohydrolase has parent Tumor Suppressor Proteins

Graph assertions

Embed this node