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Enzyme or Coenzyme

Mannose-Binding Protein-Associated Serine Proteases

AMW:CHEM:080665

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

Biochemistry biochemical
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Mannose-Binding Protein-Associated Serine Proteases has parent Complement C3-C5 Convertases
Mannose-Binding Protein-Associated Serine Proteases has parent Serine Endopeptidases

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