Public change overview
Recent concepts
Review concepts whose canonical node records were recently created or updated.
Note: this page shows concepts with recent database timestamps. It does not provide a field-by-field edit history because the current schema does not store revision diffs.
| Concept | Change | When | Node type | Domain | Identifier |
|---|---|---|---|---|---|
| Histone Deacetylase Inhibitors Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetyla… |
Added | Drug Class | Pharmacology | AMD:CLASS:00910 | |
| HIV Fusion Inhibitors Inhibitors of the fusion of HIV to host cells, preventing viral entry. This includes compounds that block attachment of HIV ENVEL… |
Added | Drug Class | Pharmacology | AMD:CLASS:01077 | |
| HIV Integrase Inhibitors Inhibitors of HIV INTEGRASE, an enzyme required for integration of viral DNA into cellular DNA. |
Added | Drug Class | Pharmacology | AMD:CLASS:00912 | |
| HIV Protease Inhibitors Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly. |
Added | Drug Class | Pharmacology | AMD:CLASS:00941 | |
| Hydroxymethylglutaryl-CoA Reductase Inhibitors Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis. |
Added | Drug Class | Pharmacology | AMD:CLASS:00875 | |
| Hygiene Products Personal care items specifically used for hygiene and cleanliness. |
Added | Drug Class | Pharmacology | AMD:CLASS:01364 | |
| Hygroscopic Agents Materials that readily absorb moisture from their surroundings. |
Added | Drug Class | Pharmacology | AMD:CLASS:01335 | |
| Hypoglycemic Agents Substances which lower blood glucose levels. |
Added | Drug Class | Pharmacology | AMD:CLASS:01120 | |
| Hypolipidemic Agents Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. |
Added | Drug Class | Pharmacology | AMD:CLASS:00873 | |
| Immune Checkpoint Inhibitors Drugs that block negative regulator IMMUNE CHECKPOINT proteins (e.g., PD-1 RECEPTOR and CTLA-4 ANTIGEN) thereby increasing suppre… |
Added | Drug Class | Pharmacology | AMD:CLASS:00959 | |
| Immunologic Factors Biologically active substances whose activities affect or play a role in the functioning of the immune system. |
Added | Drug Class | Pharmacology | AMD:CLASS:01124 | |
| Immunomodulating Agents Agents that alter the response of the immune system by activating (IMMUNOSTIMULANT) or suppressing (IMMUNOSUPPRESSIVE) the immune… |
Added | Drug Class | Pharmacology | AMD:CLASS:01128 | |
| Immunosorbents An insoluble support for an ANTIGEN or ANTIBODIES that is used in AFFINITY CHROMATOGRAPHY to adsorb the homologous antibody or an… |
Added | Drug Class | Pharmacology | AMD:CLASS:01378 | |
| Immunosuppressive Agents Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibi… |
Added | Drug Class | Pharmacology | AMD:CLASS:01129 | |
| Incretins Peptides which stimulate INSULIN release from the PANCREATIC BETA CELLS following oral nutrient ingestion, or postprandially. |
Added | Drug Class | Pharmacology | AMD:CLASS:01118 | |
| Indicators and Reagents Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions.… |
Added | Drug Class | Pharmacology | AMD:CLASS:01343 | |
| Insect Repellents Substances causing insects to turn away from them or reject them as food. |
Added | Drug Class | Pharmacology | AMD:CLASS:01168 | |
| Insecticides Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease v… |
Added | Drug Class | Pharmacology | AMD:CLASS:01306 | |
| Insulin Secretagogues Hypoglycemic agents that stimulate INSULIN SECRETION from the PANCREATIC BETA CELL to decrease postprandial BLOOD GLUCOSE. |
Added | Drug Class | Pharmacology | AMD:CLASS:01122 | |
| Integrase Inhibitors Compounds which inhibit or antagonize biosynthesis or actions of integrase. |
Added | Drug Class | Pharmacology | AMD:CLASS:00911 | |
| Intercalating Agents Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deformi… |
Added | Drug Class | Pharmacology | AMD:CLASS:01348 | |
| Interferon Inducers Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic poly… |
Added | Drug Class | Pharmacology | AMD:CLASS:01134 | |
| Interleukin Inhibitors IMMUNOSUPPRESSIVE AGENTS which inhibit the action of INTERLEUKINS. |
Added | Drug Class | Pharmacology | AMD:CLASS:01131 | |
| Interleukin-6 Inhibitors Immunosuppressive agents which inhibit the action of INTERLEUKIN-6. |
Added | Drug Class | Pharmacology | AMD:CLASS:01132 | |
| Ion Exchange Resins High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ION … |
Added | Drug Class | Pharmacology | AMD:CLASS:01352 | |
| Ionic Liquids Salts that melt below 100 C. Their low VOLATILIZATION can be an advantage over volatile organic solvents. |
Added | Drug Class | Pharmacology | AMD:CLASS:01372 | |
| Ionophores Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are … |
Added | Drug Class | Pharmacology | AMD:CLASS:00964 | |
| Iron Chelating Agents Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed i… |
Added | Drug Class | Pharmacology | AMD:CLASS:01071 | |
| Irritants Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are ru… |
Added | Drug Class | Pharmacology | AMD:CLASS:01336 | |
| Janus Kinase Inhibitors Agents that inhibit JANUS KINASES. |
Added | Drug Class | Pharmacology | AMD:CLASS:00943 |