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Public change overview

Recent concepts

Review concepts whose canonical node records were recently created or updated.

5,576 concepts

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ConceptChangeWhenNode typeDomainIdentifier
Dark Adaptation
Adjustment of the eyes under conditions of low light. The sensitivity of the eye to light is increased during dark adaptation.
Updated State Physiology AMW:PHYS:140004
Dealkylation
The removing of alkyl groups from a compound. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Updated Biochemical Process Physiology AMW:PHYS:020048
DNA Replication Timing
The temporal order in which the DNA of the GENOME is replicated.
Updated Biochemical Process Physiology AMW:PHYS:020063
Excitation Contraction Coupling
A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize an…
Updated Physiological Process Physiology AMW:PHYS:020306
Genetic Fitness
The capability of an organism to survive and reproduce. The phenotypic expression of the genotype in a particular environment det…
Updated State Physiology AMW:PHYS:050080
Genetic Variation
Genotypic differences observed among individuals in a population.
Updated State Physiology AMW:PHYS:050324
Genomic Structural Variation
Contiguous large-scale (1000-400,000 basepairs) differences in the genomic DNA between individuals, due to SEQUENCE DELETION; SEQ…
Updated State Physiology AMW:PHYS:050373
Molecular Conformation
The characteristic three-dimensional shape of a molecule.
Updated State Physiology AMW:PHYS:020162
Nutritional Status
State of the body in relation to the consumption and utilization of nutrients.
Updated State Physiology AMW:PHYS:070346
Organism Hydration Status
Quantitative measure of water or fluids contained in the body of a living organism.
Updated State Physiology AMW:PHYS:070464
Phase Variation
An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly …
Updated State Physiology AMW:PHYS:050371
Physical Fitness
The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical …
Updated State Physiology AMW:PHYS:110057
Polymorphism, Single-Stranded Conformational
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragmen…
Updated State Physiology AMW:PHYS:050378
Transfer RNA Aminoacylation
The conversion of uncharged TRANSFER RNA to AMINO ACYL TRNA.
Updated Biochemical Process Physiology AMW:PHYS:020010
Viral Replication Compartments
Sites in the host cell where the virus induces the formation of cellular assemblies for the replication of the VIRAL GENOME.
Updated Biochemical Process Physiology AMW:PHYS:060068
Virus Latency
The ability of a pathogenic virus to lie dormant within a cell (LATENT INFECTION). In eukaryotes, subsequent activation and viral…
Updated State Physiology AMW:PHYS:060075
DNA Sequence, Unstable
A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature…
Added Nucleic Acid Related Biochemistry AMW:CHEM:130174
Electrons
Stable elementary particles having the smallest known negative charge, present in all elements; also called negatrons. Positively…
Added Inorganic Chemical Biochemistry AMW:CHEM:010477
Genes, rRNA
Genes, found in both prokaryotes and eukaryotes, which are transcribed to produce the RNA which is incorporated into RIBOSOMES. P…
Added Nucleic Acid Related Biochemistry AMW:CHEM:130178
Neutrons
Electrically neutral elementary particles found in all atomic nuclei except light hydrogen; the mass is equal to that of the prot…
Added Inorganic Chemical Biochemistry AMW:CHEM:010478
Protein Structural Elements
Distinguishing three-dimensional structures characteristically formed by homologous protein sequences.
Added Peptide or Protein Biochemistry AMW:CHEM:122678
Regulatory Elements, Transcriptional
Nucleotide sequences of a gene that are involved in the regulation of GENETIC TRANSCRIPTION.
Added Nucleic Acid Related Biochemistry AMW:CHEM:130176
Replication Origin
A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It co…
Added Nucleic Acid Related Biochemistry AMW:CHEM:130175
RNA 5' Terminal Oligopyrimidine Sequence
A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is…
Added Nucleic Acid Related Biochemistry AMW:CHEM:130173
Transcription Initiation Site
The first nucleotide of a transcribed DNA sequence where RNA polymerase (DNA-DIRECTED RNA POLYMERASE) begins synthesizing the RNA…
Added Nucleic Acid Related Biochemistry AMW:CHEM:130177
Vitamin D Response Element
A DNA sequence that is found in the promoter region of vitamin D regulated genes. Vitamin D receptor (RECEPTOR, CALCITRIOL) binds…
Added Nucleic Acid Related Biochemistry AMW:CHEM:130172
DNA Copy Number Variations
Stretches of genomic DNA that exist in different multiples between individuals. Many copy number variations have been associated …
Updated State Physiology AMW:PHYS:050374
DNA Cleavage
A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone…
Updated Biochemical Process Physiology AMW:PHYS:020053
DNA Repeat Expansion
An increase number of repeats of a genomic, tandemly repeated DNA sequence from one generation to the next.
Updated Biochemical Process Physiology AMW:PHYS:020142
Nucleic Acid Conformation
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
Updated State Physiology AMW:PHYS:020164